Ibuprofen in the first three months of pregnancy may harm future fertility of baby girls

Pregnant women who take the pain killer ibuprofen in the first three months of pregnancy may be reducing the store of eggs in the ovaries of their daughters. Researchers have found the first evidence in human ovarian tissue that exposure to ibuprofen during the crucial first three months of foetal development results in a “dramatic loss” of the germ cells that go into making the follicles from which female eggs develop. The germ cells either died or failed to grow and multiply at the usual rate. The authors of the study, which is published today (Friday) in Human Reproduction1, one of the world’s leading reproductive medicine journals, say that their findings raise concerns about the long-term effects of ibuprofen on the future fertility of women exposed to the pain killer when in their mothers’ wombs. “Baby girls are born with a […]