Cancer-fighting nanorobots programmed to seek and destroy tumors

In a major advancement in nanomedicine, Arizona State University (ASU) scientists, in collaboration with researchers from the National Center for Nanoscience and Technology (NCNST), of the Chinese Academy of Sciences, have successfully programmed nanorobots to shrink tumors by cutting off their blood supply. “We have developed the first fully autonomous, DNA robotic system for a very precise drug design and targeted cancer therapy,” said Hao Yan, director of the ASU Biodesign Institute’s Center for Molecular Design and Biomimetics and the Milton Glick Professor in the School of Molecular Sciences. “Moreover, this technology is a strategy that can be used for many types of cancer, since all solid tumor-feeding blood vessels are essentially the same,” said Yan. The successful demonstration of the technology, the first-of-its-kind study in mammals utilizing breast cancer, melanoma, ovarian and lung cancer mouse models, was published in […]

Breastfeeding reduces hypertension risk

A study published in the American Journal of Hypertension indicates that women who breastfeed more children, and for longer periods of time, are less likely to suffer from hypertension after they reach menopause. This is less true of obese women, however. Elevated blood pressure is the greatest single risk factor for disease and mortality. Evidence from epidemiologic data has also shown the beneficial effects of breastfeeding on the health of infants and their mothers. It has been well documented that long-term breastfeeding is associated with reduced children’s allergies, celiac disease, obesity, and diabetes mellitus. However, the effects of breastfeeding on maternal health have been little studied compared with the effects on the children. Several studies consistently found that absent breastfeeding or premature discontinuation was associated with increased risks of diabetes mellitus, dyslipidemia, metabolic syndrome, coronary heart disease, and cardiovascular diseases. However few […]

Study finds bacteria in milk linked to rheumatoid arthritis

A strain of common bacteria in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida. A team of UCF College of Medicine researchers has discovered a link between rheumatoid arthritis and Mycobacterium avium subspecies paratuberculosis, known as MAP, a bacteria found in cows. The bacteria can be spread to humans through the consumption of infected milk, beef and produce fertilized by cow manure. The UCF researchers are the first to report this connection between MAP and rheumatoid arthritis in a study published in the Frontiers in Cellular and Infection Microbiology journal this week. The study, funded in part by a $500,000 grant from the Florida Legislative, was a collaboration between Saleh Naser, UCF infectious disease specialist, Dr. Shazia Bég, rheumatologist at UCF’s […]

Scientists make cells that enable the sense of touch

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons — the cells that give us our sense of touch. The new protocol could be a step toward stem cell-based therapies to restore sensation in paralyzed people who have lost feeling in parts of their body. The study, which was led by Samantha Butler, a UCLA associate professor of neurobiology and member of the Broad Stem Cell Research Center, was published today in the journal Stem Cell Reports. Sensory interneurons, a class of neurons in the spinal cord, are responsible for relaying information from throughout the body to the central nervous system, which enables the sense of touch. The lack of a sense of touch greatly affects people who are paralyzed. […]

Proper exercise can reverse damage to aging hearts

Exercise can reverse damage to  aging hearts and help prevent risk of future heart failure — if it’s enough exercise, and if it’s begun in time, according to a new study by cardiologists at UT Southwestern and Texas Health Resources. To reap the most benefit, the exercise regimen should begin by late middle age (before age 65), when the heart apparently retains some plasticity and ability to remodel itself, according to the findings by researchers at the Institute for Exercise and Environmental Medicine (IEEM), which is a collaboration between UT Southwestern Medical Center and Texas Health Presbyterian Hospital Dallas. And the exercise needs to be performed four to five times a week. Two to three times a week was not enough, the researchers found in an earlier study. “Based on a series of studies performed by our team over the […]